This is funny, since I was just talking to a coworker about this earlier today. My wife would have first dibs on everything of course, but since she's more of an SNES and PS1 RPG person, she probably wouldn't want the bulk of my collection, which is Sega stuff.
I'd have all my Sega consoles and games that she wouldn't want go to a close friend of mine who's a old school gamer. Heh, he'd finally be able to play all those Sega CD adventure games he's always eyed.