Other M's gameplay wasn't bad. It wasn't perfect, but for a first attempt the actual gameplay wasn't a bad direction. It was the story, linearity to rival Metroid II, voice acting, and whatnot that really ruined the game. So I wouldn't mind them giving it a second go, though it might be too painful for people still scarred by M:OM.
I prefer 2D personally. But I never got into the Prime series. Maybe I would have if I had gotten my hands on the Trilogy, but c'est la vie.