As someone who put out some serious cash to own a legit copy of Little Samson I would be annoyed if reproductions which were indistinguishable from a legit copy hit the market.
First off I will say that I don't care if the value of the game drops to less that what I paid. I have a budget for collecting that I stick to so the money isn't a big deal. If Samson got a 3ds remake and it dropped the market value of the game so be it.
I just think it would wreck the collector market and the fun of the hobby if there was an added burden of trying to figure out if what you are buying is real or not.
Also, like others have said, the thrill of the hunt would be diminished and if you did find a copy in the wild how do you know if it's official or not?
If someone wants to experience the game on the original hardware (which I totally get) they can:
1. get one of those retrozone power pack things
2. look for an international version which may be cheaper as there is not much text in the game and acquire an international system or get a converter
3. I would support a repro if the fact that it was a repro was marked on the shell, the inside of the cart, and on the label, and the label had different art work than the retail release
As others have stated, I'd prefer repros be limited to games that were not released here (North America) especially for text heavy games such as RPGs where understanding the dialogue in the game is necessary to complete it.